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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
135
Publications avec texte intégral
Open Access
53 %
Mots clés
Cell penetrating peptide
Myotonic dystrophy
Muscle
RNA splicing
ACETYLCHOLINESTERASE
Cytoskeleton
Glutamate
RNA interference
Neuron
Knockout
Myotonic dystrophy type 1
MBNL
Trinucleotide repeat expansion
Genotype phenotype correlation
Thérapie génique
CTG repeat contractions
Aging
Dilated cardiomyopathy
Gene therapy
Oligodendrocyte
Heart
Transgenic mouse
Astrocytes
Mice
Dystrophin
CMS
CTG repeats
PCR
GABA
Dystrophie myotonique
Diaphragm
Therapy
GSK3
Antisense oligonucleotide
Skeletal muscle
Dystrophie Myotonique
Myotonic Dystrophy type 1
Male
Dynamin 2
RNA biology
Brain dysfunction
Myostatin
Cardiac muscle
Acetylcholinesterase knockout mouse
Cell culture model
Transcriptomics
Centronuclear myopathy
Antisense oligonucleotides
Humans
CONGENITAL MYATHENIC SYNDROME
Brain
DMPK
Trinucleotide Repeat Expansion
Motoneuron
DM1
ARN
Myotonic Dystrophy
Mouse model
Maximal force
Alternative splicing
Myotonic dystrophy mouse models
Cell model
Exercise
PacBio
Exercice
Intermediate filament
Autophagy
Fibrosis
Glial cells
In vivo
CRISPR/Cas9
KNOCKOUT MICE
CRISPRi
Acetylcholinesterase deficiency
Expression
Glucocorticoid-receptor
Duchenne muscular dystrophy
Endurance training
Animals
CTG repeat instability
Acute coronary syndrome
Long read sequencing
Glucocorticoids
Quantitative microdialysis
Muscular dystrophy
Heart failure
Mouse models
Hypoxia
Myotonic Dystrophy Type 1
Myelin
Oligodendrocytes
Transgenic mouse model
Astrocyte
Desmin
DMSXL mice
BIOLOGIE MOLECULAIRE
Central nervous system
Gene Therapy
Gene editing
AAV